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Subscribers may share up to 10 or 20 articles per month using the gift article service. More information can be found at Like millions of middle-aged people, Kindlerís chances of enjoying a longer, healthier life have been transformed by atorvastatin, his cholesterol-reducing treatment, which has helped shift medical practice from offering acute treatment for small groups of patients with severe heart problems to long-term preventive care for the masses.

Research findings dating back to the 1990s show that serum cholesterol level, especially the HDL fraction, is significantly lower in many patients with major depressive disorder than in matched non-depressed individuals and that clinical improvement following antidepressant therapy is often associated with normalization of serum total cholesterol to higher levels

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